Developed at UCLA and licensed exclusively to Protein Pathways, the DIP Database catalogs protein-protein interactions that have been experimentally determined and described in published papers.
Each database record includes information on the experimental methods used to determine the interaction, literature references, and, when available, the portion of the protein (amino acid residues or domain) that interacts and the dissociation constant of the interaction.
Each protein in the DIP database has a unique identifier, which is cross-referenced to identifiers from SWISS-PROT (from the Swiss Institute of Bioinformatics and the European Bioinformatics Institute), PIR (Protein Information Resource), NCBI (National Center for Biotechnology Information), and PDB (Protein Data Bank).
Unlike other databases that contain sequence or annotation information about single proteins, the DIP™ Database focuses entirely on experimental interactions between pairs of proteins.
The DIP Database combines many different sources of literature information, all of which have been both automatically and manually checked by the DIP™ Database curator. Interaction information combined from different experimental sources leads to the construction of large networks of interacting proteins.
The DIP™ Database is free for academic institutions and available to commercial users for a fee. Please contact us for licensing information, email@example.com.
To learn more about the database, evaluation access is available to all commercial users. Visit the DIP™ Database website.